Prof. Dr. Stephan Schmitz

Prof. Dr. Stephan Schmitz

Wissenschaftlicher Leiter FHM Pulheim
Naturwissenschaftliche Grundlagen
stephan.schmitz@@fh-mittelstand.de

Wirtschaft
Pulheim (bei Köln)

Publikationen

  • Schmitz S, Schaap I, Kleinjung J, Harder S, Grainger M, Calder L, Rosenthal P, Holder A & Veigel C (2010) Malaria parasite actin polymerization and filament structure. J Biol Chem 285:36577-36585
  • Albet-Torres N, Bloemink MJ, Barman T, Candau R, Frölander K, Geeves MA, Golker K, Herrmann C, Lionne C, Piperio C, Schmitz S, Veigel C & Mansson A (2009) Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin. J Biol Chem 284:22926-22937
  • Schmitz S, Smith-Palmer J, Sakamoto T, Sellers JR & Veigel C (2006) Walking mechanism of the intracellular cargo transporter myosin V. J Phys-Condens Mat 18:1943-1946
  • Veigel C, Schmitz S, Wang F & Sellers JR (2005) Load-dependent kinetics of myosin-V can explain its high processivity. Nature Cell Biol 7:854-856
  • Molloy JE & Schmitz S (2005) Molecular motors: kinesin steps back. Nature 435:285-287 (Comment)
  • Schmitz S, Grainger M, Howell S, Calder LJ, Gaeb M, Pinder JC, Holder AA & Veigel C (2005) Malaria parasite actin filaments are very short. J Mol Biol 349:113-125
  • Roberts R, Lister I, Schmitz S, Walker M, Veigel C, Trinick J, Buss F & Kendrick-Jones J (2004) Myosin VI: cellular functions and motor properties. Philos Trans R Soc Lond B Biol Sci 359:1931-1944
  • Lister I, Schmitz S, Walker M, Trinick J, Buss F, Veigel C & Kendrick-Jones J (2004) A monomeric myosin VI with a large working stroke. EMBO J 23:1729-1738
  • Lister I, Roberts R, Schmitz S, Walker M, Trinick J, Veigel C, Buss F & Kendrick-Jones J (2004) Myosin VI: a multifunctional motor. Biochem Soc Trans 32:685-688
  • Burgess S, Walker M, Knight PJ, Sparrow J, Schmitz S, Offer G, Bullard B, Leonard K, Holt J & Trinick J (2004) Structural studies of arthrin: monoubiquitinated actin. J Mol Biol 341:1161-1173
  • Veigel C, Molloy JE, Schmitz S & Kendrick-Jones J (2003) Load dependent kinetics of force production by smooth muscle myosin, measured using optical tweezers. Nature Cell Biol 5:980-986
  • Schmitz S, Schankin CJ, Prinz H, Curwen RS, Ashton PD, Caves LSD, Fink RHA, Sparrow JC, Mayhew PJ & Veigel C (2003) Molecular evolutionary convergence of the flight muscle protein arthrin in Diptera and Hemiptera. Mol Biol Evol 20:2019-2033
  • Sakamoto T, Wang F, Schmitz S, Molloy JE, Veigel C & Sellers JR (2003) Neck length and processivity of myosin V. J Biol Chem 278:29201-29207
  • Schmitz S & Veigel C (2002) Size matters: Mechanics of Motor Proteins and the Cytoskeleton. J Cell Sci 115:2807-2808 (book review)
  • Ruegg JC, Veigel C, Molloy JE, Schmitz S, Sparrow JC & Fink RHA (2002) Molecular motors: Force and movement generated by single myosin-II molecules. News Physiol Sci 17:213-218
  • Schmitz S, Clayton J, Nongthomba U, Veigel C, Geeves MA & Sparrow JC (2000) Drosophila Act88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function. J Mol Biol 295:201-210
  • Razzaq A, Schmitz S, Veigel C, Molloy JE, Geeves MA & Sparrow JC (1999) Actin residue E93K is identified as an amino acid affecting myosin binding. J Biol Chem 274:28321-28328
  • Schmitz S (1999) Mutational analysis of proposed myosin binding sites on actin. DPhil thesis Univ. York